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Addyi (Flibanserin)

placebo in premenopausal women with HSDD who showed a predefined response after 24 weeks of open-label treatment with Addyi. Naturally postmenopausal women were randomly assigned to receive Addyi (100 mg/d) or placebo. Effect of Addyi (BIMT 17), fluoxetine, 8-OH-DPAT and buspirone on serotonin synthesis in rat brain.

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Addyi is used to treat women with hypoactive sexual desire disorder (HSDD; a low sexual desire that causes distress or interpersonal difficulty) who have not experienced menopause (change of life; the end of monthly menstrual periods). Addyi should not be used for the treatment of HSDD in women who have gone through menopause or in men or to improve sexual performance. Addyi is in a class of medications called a serotonin receptor 1A agonist/serotonin receptor 2A antagonist. It works by changing the activity of serotonin and other natural substances in the brain.

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