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Actinum (Oxcarbazepine)
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Oxcarbazepine

Actinum is a new anticonvulsant with an active metabolite. It is approved as mono- or adjunctive therapy for partial seizures in adults and children older than 4 years of age and as adjunctive therapy in children 2 years and older. Its spectrum of anticonvulsant activity is comparable to carbamazepine, but it has an improved pharmacokinetic profile, is better tolerated and is associated with few clinically significant drug-drug interactions.

Other names for this medication:
Oxcarbazepine, Trileptal, Actinum, Apydan, Auram, Aurene, Deprectal, Leptal, Oxcarbazepin, Oxcarbazepina, Oxetol, Oxicodal, Tolep,

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Actinum comes as a tablet, an extended-release tablet, and a suspension (liquid) to take by mouth. The tablet and suspension are usually taken every 12 hours (twice a day) with or without food. The extended-release tablet is usually taken once a day on an empty stomach, 1 hour before or 2 hours after a meal. Take Actinum at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Actinum exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Shake the suspension well right before each use to mix the medication evenly. Use the oral dosing syringe that came with the medication to withdraw the right amount of suspension from the bottle. You can swallow the suspension straight from the syringe or you can mix it with a small glass of water and swallow the mixture. Wash the syringe with warm water and allow it to dry thoroughly after use.

Swallow the extended-release tablets whole with water or another liquid; do not split, chew, or crush them.

Your doctor will probably start you on a low dose of Actinum and gradually increase your dose, not more often than once every 3 days. If you were taking another medication to treat your seizures and are switching to Actinum, your doctor may gradually decrease your dose of the other medication while increasing your dose of Actinum. Follow these directions carefully and ask your doctor if you are not sure how much medication you should take.

Actinum may help control your seizures but will not cure your condition. Continue to take Actinum even if you feel well. Do not stop taking Actinum without talking to your doctor, even if you experience side effects such as unusual changes in behavior or mood. If you suddenly stop taking Actinum, your seizures may get worse. Your doctor will probably decrease your dose gradually.

Your doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with Actinum and each time you refill your prescription. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also visit the Food and Drug Administration (FDA) website (http://www.fda.gov/Drugs) or the manufacturer's website to obtain the Medication Guide.

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Patient-specific loading was found to be the primary contributor to joint loading and kinematics during low flexion, particularly under conditions of high external loads (for instance, the gait cycle with high internal-external torque), while design and surgical factors, particularly femoral posterior radius and posterior slope of the tibial insert became increasingly important in TKR performance in deeper flexion. We present a simple and cost-effective technique that aids in the maintenance of pneumoretroperitoneum. Developing a measure of health care service quality is an important precursor to systems and organizations that value health care quality.

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The organisation and rehabilitation of the post myocardial infarction patient. Characterization and improvement of apple extracts for the diagnosis of apple IgE-mediated allergy. The fatty acid profile of dietary fats may contribute to its channelling toward oxidation versus storage, influencing energy and weight balance. The length of poly(C) stretch in the Bordetella pertussis Pfim3 promoter determines the vag or vrg function of the fim3 gene.

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Patients with criteria of rapid care alert (RCA) without treatment, cardiac arrest (CA), and unexpected ward deaths (UWD), during 2010. The summary estimate of the incidence of PPH among women with placenta previa was considerable in this systematic review. Omental torsion though rare, should be included in the differential diagnosis of acute abdomen.

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11C-(R)-Rolipram binding in the brain was measured using arterial 11C-(R)-rolipram levels to correct for the influence of cerebral blood flow. Consequently, the data obtained provided a reliable target region for future agonist/inverse agonist studies on AlstRs. Compressibility Anisotropy and Electronic Properties of Oxyanionic Hydrates. To assess the accuracy of a novel digital templating methodology for total hip arthroplasty (THA) in patients with osteonecrosis of the femoral head (ONFH). Nutritional assessment and intervention in a pediatric oncology unit.

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Spermatozoa were found most abundantly between the mucosal folds. Noninvasive stroke volume variation using electrical velocimetry for predicting fluid responsiveness in dogs undergoing cardiac surgery. Fast lung nodule detection in chest CT images using cylindrical nodule-enhancement filter. To determine whether self-reported pain measures are associated with selection for multimodal or multidisciplinary rehabilitation (MMR) and whether this selection is influenced by sex.

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Long-term disease stabilization following treatment with erlotinib in heavily pretreated patients with wild-type epidermal growth factor receptor non-small-cell lung carcinoma: Two case reports. The PIWI protein acts as a predictive marker for human gastric cancer. Little or no evidence for the effectiveness or cost-effectiveness of any of the interventions to reduce repeat pregnancy in young women was found.

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A proton magnetic resonance study of the aggregation of actinomycin D in D 2 O. Report of a survey on 1000 asymptomatic neuropsychiatric patients. Radon potential maps that account for geologic factors and observed radon values may be superior to using observed radon values only. The bacterium Geobacter sulfurreducens is a model biological catalyst in microbial electrochemical devices. On some problems of methodology of scientific research in outpatient public health institutions

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This study proposed to determine the prevalence of substance use and drug-related arrests among caregivers of children referred to Child Protective Services (CPS), examine the relationship between substance use and arrests among caregivers, and examine the main effects and interaction of substance use and arrests in predicting child trauma exposure. The vaccination coverage among children aged 24 - 30 months in pediatric offices November 1999 - May 2001. There was little correlation between in vitro secretory activity and total ecdysone in circulation.

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The aim of the study was to evaluate the socio-demographic factors associated with initiation of regular smoking among adults. One of the most discomfortable dose-limiting adverse reactions of effective drugs for the treatment of solid tumors is a peripheral neuropathy which is the main reason for dose reduction and discontinuation of the therapy. To report the presence of viable mycobacteria in a patient with keratitis treated for 6 months. Monitoring Antifungal Resistance in a Global Collection of Invasive Yeasts and Molds: Application of CLSI Epidemiological Cutoff Values and Whole-Genome Sequencing Analysis for Detection of Azole Resistance in Candida albicans. Studies on the use of inhalation anesthesia in diagnosis and therapy as well as scientific research

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A 23-year-old man with a left intraventricular hemangiopericytoma presenting with headache, word-finding difficulties, blurred vision, nausea, vomiting, photophobia, and right-sided weakness and numbness. Critical role of Keratin 1 in maintaining epithelial barrier and correlation of its down-regulation with the progression of inflammatory bowel disease. However, hydroxyurea underutilization and adherence remain challenges for patients with SCD. Investigation on chemical species of arsenic, selenium and antimony in fly ash from coal fuel thermal power stations.

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