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The effects of Isosorbide dinitrate (ISDN) and its 2- and 5-mononitrate metabolites (2-ISMN and 5-ISMN) against platelet aggregation and thromboxane release were investigated by analysis of platelet aggregation curves. Combined with hydralazine, chronic oral administration of Isosorbide dinitrate has been demonstrated to improve survival when added to digoxin and diuretic therapy.

Other names for this medication:
Isosorbide, Isordil,

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Isosorbide immediate-release tablets are used for the management of angina (chest pain) in people who have coronary artery disease (narrowing of the blood vessels that supply blood to the heart). Isosorbide extended-release (long-acting) tablets and extended-release capsules are used for the management of chest pain in people who have coronary artery disease. Isosorbide can only be used to prevent angina; it cannot be used to treat an episode of angina once it has begun. Isosorbide is in a class of medications called vasodilators. It works by relaxing the blood vessels so the heart does not need to work as hard and therefore does not need as much oxygen.

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A comparison of the post-mortem blood-alcohol levels of drivers and passengers compared with those of drinking drivers who kill pedestrians. These results indicated that elevated temperature has diverse effects on mitogen-induced lymphocyte functions in vitro. Should patients with acute myocardial infraction be transferred to a tertiary center for primary angioplasty or receive it at qualified hospitals in the community? The interventions, which included provision of meaningful, enjoyable, and interactive activities, anticipatory strategies, and calming strategies, significantly influenced the dependent variables and are described in detail. Interestingly a fivefold reduction in the growth of BCC in nude mice was observed if D3 expression was knocked down.

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Additional evaluation of this therapeutic approach is warranted. Transfracture medial transposition of the radial nerve associated with plate fixation of the humerus. Reverse breech extraction versus head pushing to facilitate delivery of the deeply impacted fetal head.

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Increased regulatory T cell graft content is associated with improved outcome in haematopoietic stem cell transplantation: a systematic review. Best practices include establishing a culture of health and using strategic communications. Drug resistance remains a major clinical obstacle to successful treatment of cancer. In this study, we examined the role of AR in regulating the growth and the phagocytic activity of bone marrow-derived mouse macrophages (BMMs) from AR-null and wild-type (WT) mice.

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Correlative study of blood coagulation and serum lipids in diabetics without clinically recognizable complications. The different relative subdomain orientations observed for the NC and C states highlight the large conformational flexibility of the HK domain. Although hymenoptera-induced anaphylaxis is not primarily a mast cell-driven hematological disorder, the latter is present in a significant proportion of patients and has to be excluded by basal serum tryptase determination, skin inspection as well as exclusion of systemic mastocytosis by D816V mutation analysis in peripheral blood and/or bone marrow examination in selected patients.

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A 31-year-old male presenting with intracranial hemorrhage manifesting as deep coma and anisocoria underwent immediate emergency surgery. The results showed that nonwoven flax fibre geotextiles can increase flow homogeneity. This condition remained stable for over 2 months although haematoma size decreased significantly.

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